Page 26 - Micro5 Brochure 2017

animal in the lab, he could measure the changes of the electrical patterns at
the stump over several days as it went through healing and repair.
In studying the complex regeneration of tissues, Becker was able to identify
the repair mechanisms between salamanders and frogs during healing of
injuries. Frogs and Salamanders are in the evolutionary genetic stage part,
however, salamanders can regrow limbs while frogs are not able to do so.
This shows that frogs have lost the ability to regenerate during the
evolutionary process on their genetic journey in the amphibian
family tree. The scientist was keen in looking at the electrical changes during
the 'current of injury' with the stumps of salamanders that could regrow their
legs and with frogs that could not.
So Becker would amputate the limbs of salamanders and frogs. He would use
electrodes to measure the electrical potential at the point of healing. The frogs
would show a positive electrical potential that would eventually drift to a zero
or neutral potential as the stump healed over. I created the following diagram
to highlight this explanation.

Observing The "Current Of Injury" In Experimental Amputation
In the case of the salamander, the electrical potential at the stump would be
the same like the frog initially. However, this positive polarity, would then
switch to a negative vibration during the course of healing. This electrical
negative potential would then drift to a zero or neutral point during a period of
days, as the salamander grows back a new leg.