Page 48 - Micro5 Brochure 2017

Ultra-low microcurrent in the management of diabetes mellitus,
hypertension and chronic wounds: report of twelve cases and
discussion of mechanism of action.

Lee BY, Al-Waili N, Stubbs D, Wendell K, Butler G, Al-Waili T, Al-Waili A.

Source

Department of Surgery, New York Medical College, Valhalla, New York, USA.
BYLee2100@aol.com

Abstract

Oxidative stress plays a major role in the pathogenesis of both types of diabetes mellitus and
cardiovascular diseases including hypertension. The low levels of antioxidants accompanied by
raised levels of markers of free radical damage play a major role in delaying wound healing.
Ultra-low microcurrent presumably has an antioxidant effect, and it was shown to accelerate
wound healing. The purpose of the study is to investigate the efficacy of ultra-low microcurrent
delivered by the Electro Pressure Regeneration Therapy (EPRT) device (EPRT Technologies-
USA, Simi Valley, CA) in the management of diabetes, hypertension and chronic wounds. The
EPRT device is an electrical device that sends a pulsating stream of electrons in a relatively low
concentration throughout the body. The device is noninvasive and delivers electrical currents that
mimic the endogenous electric energy of the human body. It is a rechargeable battery-operated
device that delivers a direct current (maximum of 3 milliAmperes) of one polarity for 11.5
minutes, which then switched to the opposite polarity for another 11.5 minutes. The resulting
cycle time is approximately 23min or 0.000732 Hz and delivers a square wave bipolar current
with a voltage ranging from 5V up to a maximum of 40 V. The device produces a current range
of 3 mA down to 100 nA. Twelve patients with long standing diabetes, hypertension and
unhealed wounds were treated with EPRT. The patients were treated approximately for 3.5
h/day/5 days a week. Assessment of ulcer was based on scale used by National Pressure Ulcer
Advisory Panel Consensus Development Conference. Patients were followed-up with daily
measurement of blood pressure and blood glucose level, and their requirement for medications
was recorded. Treatment continued from 2-4 months according to their response. Results showed
that diabetes mellitus and hypertension were well controlled after using this device, and their
wounds were markedly healed (30-100%). The patients either reduced their medication or
completely stopped after the course of treatment. No side effects were reported. The mechanism
of action was discussed.

PMID:

20046232

[PubMed - indexed for MEDLINE]

PM R. 2009 Aug;1(8):736-9. doi: 10.1016/j.pmrj.2009.06.008.