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Evaluation of the effects of electrical stimulation on cartilage repair in
adult male rats.
Zuzzi DC, Ciccone Cde C, Neves LM, Mendonça JS, Joazeiro PP, Esquisatto MA.
Source
Programa de Pós-graduação em Ciências Biomédicas, Centro Universitário Hermínio Ometto, Av. Dr.
Maximiliano Baruto, 500 Jd. Universitário, 13607-339 Araras, SP, Brazil.
Abstract
This study describes the organization of mature hyaline xiphoid cartilage during repair in animals
submitted to electrical current stimulation. Twenty male Wistar rats, 90 days old, were divided into a
control group (CG) and a treated group (TG). A cylindrical full-thickness cartilage defects were created
with a 3-mm punch in anesthetized animals. After 24h, TG received daily applications of a continuous
electrical current (1Hz/20μA) for 5min. The animals were sacrificed after 7, 21 and 35 days for structural
analysis. In CG, the repair tissue presented fibrous characteristics, with fibroblastic cells being infiltrated
and permeated by blood vessels. Basophilic foci of cartilage tissue were observed on day 35. In TG, the
repair tissue also presented fibrous characteristics, but a larger number of thick collagen fibers were seen
on day 21. A large number of cartilaginous nests were observed on day 35. Cell numbers were
significantly higher in TG. Calcification points were detected in TG on day 35. There was no difference in
elastic fibers between groups. Ultrastructural analysis revealed the presence of chondrocyte-like cells in
CG at all time points, but only on days 21 and 35 in TG. The amount of cuprolinic blue-stained
proteoglycans was higher in TG on day 35. Microcurrent stimulation accelerates the repair process in
non-articular hyaline cartilage.
Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.
Plast Surg Nurs. 2013 Jan;33(1):6-8; quiz 9-10. doi: 10.1097/PSN.0b013e3182844219.
The use of targeted MicroCurrent Therapy in postoperative pain
management.
Gabriel A, Sobota R, Gialich S, Maxwell GP.
Source
Department of Plastic Surgery, Loma Linda University Medical Center, Loma Linda, California, USA.
Abstract
Effective postoperative analgesia is a prerequisite to enhance the recovery process and reduce morbidity.
The use of local anesthetic techniques is well documented to be effective, but single-dose techniques
(infiltration, peripheral blocks, neuraxial blocks) have been of limited value in major operations because of
their short duration of analgesia. Recent advances in technology have led to the development of a
noninvasive device, targeted MicroCurrent Therapy, which enhances postsurgical recovery by stimulating
the body's natural healing process. This therapy transmits gentle, short bursts of electrical current
