Page 62 - Micro5 Brochure 2017

Effect of microcurrent electrical stimulation on tendon healing
tendons. The healing of surgically induced wound may differ
from a tendon ruptures due to stress or loading. So this issue
could be studied in future research.
So it can be concluded that, for improving the healing of
surgically repaired rabbits tendons, application of cathodal
MES in the early stage could result in more beneficial effects
on biomechanical and histopathological properties rather than
anodal MES, while anodal MES application could produce
better results than cathodal later at late stage of healing. So,
in light of the present study, it may be germane to adjust the
MES polarity differently for the different stages of healing to
obtain optimal effects. Further studies investigating the effects
of combination of cathodal polarity of MES at early phase of
tendon healing, then switching to anodal polarity are needed.
References
[1] Goodship AE, Birch HL, Wilson AM. The pathobiology and
repair of tendon and ligament injury. Vet Clin North Am Equine
Pract 1994;10(2):323–49.
[2] Enwemeka CS. Inflammation, cellularity and fibrillogenesis in
regenerating tendon: implications for tendon rehabilitation.
Phys Ther 1989;69(10):816–25.
[3] Garner WL, McDonald JA, Kuhn 3rd C, Weeks PM.
Autonomous healing of chicken flexor tendons in vitro. J
Hand Surg [Am] 1988;13(5):697–700.
[4] Fujita M, Hukuda S, Doida Y. The effect of constant direct
electrical current on intrinsic healing in the flexor tendon in vitro.
An ultrastructural study of differing attitudes in epitenon cells
and tenocytes. J Hand Surg [Br] 1992;17(1):94–8.
[5] Sharma P, Maffulli N. The future: rehabilitation, gene therapy,
optimization of healing. Foot Ankle Clin 2005;10(2):383–97.
[6] Khanna A, Friel M, Gougoulias N, Longo UG, Maffulli N.
Prevention of adhesions in surgery of the flexor tendons of the
hand: What is the evidence? Br Med Bull 2009;90(1):85–109.
[7] Picker RI. Low-volt pulsed microamp stimulation: Part 1. Clin
Manage 1989;9:28–33.
[8] Cheng N, Van Hoof H, Bockx E, Hoogmartens MJ, Mulier JC,
De Dijcker FJ, et al. The effects of electric currents on ATP
generation, protein synthesis and membrane transport of rat
skin. Clin Orthop Relat Res 1982(171):264–72.
[9] Poltawski L, Watson T. Bioelectricity and microcurrent therapy
for tissue healing: A narrative review [Bioelektrycznos´ c´ i gojenie
sie tkanek pod wpywem terapii mikropradami - Przeglad
narracyjny]. Rehab Med 2010;14(3):42–52.
[10] Bayat M, Asgari Moghadam Z, Maroufi M, Rezaie FS, Bayat
M, Rakhshan M. Experimental wound healing using
microamperage electrical stimulation in rabbits. J Rehab Res
Dev 2006;43(2):219–26.
[11] Nessler JP, Mass DP. Direct-current electrical stimulation of
tendon healing in vitro. Clin Orthop Relat Res 1987(217):303–12.
[12] Akai M, Oda H, Shirasaki Y, Tateishi T. Electrical stimulation
of ligament healing. An experimental study of the patellar
ligament of rabbits. Clin Orthop Relat Res 1988(235):296–301.
117
[13] Chan HKF, Fung DTC, Ng GYF. Effects of low-voltage
microamperage stimulation on tendon healing in rats. J Orthop
Sports Phys Ther 2007;37(7):399–403.
[14] Owoeye I, Spielholz NI, Fetto J, Nelson AJ. Low-intensity
pulsed galvanic current and the healing of tenotomized rat
achilles tendons: preliminary report using load-to-breaking
measurements. Arch Phys Med Rehab 1987;68(7):415–8.
[15] Stanish WD, Rubinovich M, Kozey J, MacGillvary G. The use
of electricity in ligament and tendon repair. Phys Sports Med
1985;13(8):108–16.
[16] Gault WR, Gatens Jr PF. Use of low intensity direct current in
management of ischemic skin ulcers. Phys Ther
1976;56(3):265–9.
[17] Balakatounis KC, Angoules AG. Low-intensity electrical
stimulation in wound healing: review of the efficacy of
externally applied currents resembling the current of injury.
Eplasty 2008;8:e28.
[18] Mehmandoust FG, Torkaman G, Firoozabadi M, Talebi G.
Anodal and cathodal pulsed electrical stimulation on skin
wound healing in guinea pigs. J Rehab Res Dev
2007;44(4):611–8.
[19] Talebi G, Torkaman G, Firouzabadi M, Mofid M, Shariat S,
Kahrizi S. Effects of micro-amperage direct current stimulation
on injury potential and its relation to wound surface area in
guinea pig. Proc Annu Int Conf IEEE Eng Med Biol
2007;23(6):3516–9.
[20] Enwemeka CS. Connective tissue plasticity: ultrastructural,
biomechanical and morphometric effects of physical factors on
intact and regenerating tendons. J Orthop Sports Phys Ther
1991;14(5):198–212.
[21] Woo SL, Orlando CA, Camp JF, Akeson WH. Effects of
postmortem storage by freezing on ligament tensile behavior. J
Biomech 1986;19(5):399–404.
[22] James R, Kesturu G, Balian G, Chhabra AB. Tendon: Biology,
biomechanics, repair, growth factors and evolving treatment
options. J Hand Surg 2008;33(1):102–12.
[23] Kiernan JA. Histological and histochemical methods: theory
and practice. 3rd ed. A Hodder Arnold Publication; 2001.
[24] Parry DA, Barnes GR, Craig AS. A comparison of the size
distribution of collagen fibrils in connective tissues as a function
of age and a possible relation between fibril size distribution and
mechanical properties. Proc R Soc Lond B: Biol Sci
1978;203(1152):305–21.
[25] Becker RO, Selden G. The body electric electromagnetism and
the foundation of life. New York: William Morrow & Co. Inc.;
1985.
[26] Lampe KE. Electrotherapy in tissue repair. J Hand Ther
1998;11(2):131–9.
[27] Sharma P, Maffulli N. Tendon injury and tendinopathy: healing
and repair. J Bone Joint Surg Am 2005;87(1):187–202.
[28] Enwemeka CS, Spielholz NI, Nelson AJ. The effect of early
functional activities on experimentally tenotomized Achilles
tendons in rats. Am J Phys Med Rehab 1988;67(6):264–9.